Policy Update
Meenu Mohan
History
The inception of DBT (Department of Biotechnology) in India was in 1986, when the then Prime Minister Rajiv Gandhi established the Department of Biotechnology within the Ministry of Science and Technology, recognizing its importance for economic growth. India was one among the first countries to create a dedicated biotechnology department at that time. The groundwork was well set much earlier in 1982, when the National Biotechnology Board (NBTB) was established to pinpoint the critical areas and formulate long-term plans to build indigenous capabilities in this new emerging area.
Mandate
To ramp up the use of biotechnology, bringing progress in the field of research and development, and improvements in the production of biological science. DBT provides oversight of self-contained institutions, promotion of partnership between universities and industries, identification and establishment of Centres of Excellence for R&D and integrating programs for human resource development and it is the nodal point for international collaborations in specific areas. It lays emphasis on infrastructure development to support both R&D and production while evolving biosafety guidelines, especially for the manufacture and application of cell-based vaccines. It also encompasses becoming the node for information collection and sharing in terms of biotechnology.
Schemes and Initiatives
- To enhance zoonotic disease governance via inclusive surveillance, coordination, and better research and preparedness towards pandemics, One Health Research Consortium comprises 27 organizations involved with interconnected health systems.
Portal for biological research regulatory approval (BioRRAP)
- Common platform providing unique BioRRAP ID for a list of agencies required for research.
CTEP Conference, Travel, Exhibition, and Popular Lectures
- Provides financial assistance towards organizing Conference/ Seminar/ Symposium/ Workshop and Travel support to the researchers for presenting their papers in the conferences which are being organized outside the country.
- Development of a common database for human molecular networks for better understanding of biology related to diseases, diagnostics, and training of students. A Public-Private venture, it compiles molecular information, identifies knowledge gaps, and educates students.
- Catalogue genetic diversity of Indians by sequencing 10,000 individual genomes. This helps provide reference genome, genetic markers for diseases, and personalized medicine.
- Ethical Considerations: Informed consent, Data protection, Participants privacy
Part of Biotechnology Sector Growth Strategy (2021-2025)
- By placing India as a global bio-manufacturing destination, it aids the knowledge-driven Bio economy, which estimates $150 billion growth in the next few years.
- Key Features: Human resource and Infrastructure development, Translational research, and Norm-setting frameworks.
Biotech-Krishi Innovation Science Application Network Scheme
- To empower farmers with science-based solutions. It has served more than 1.6 lakh farmers.
- Special Features: Hub-and-spoke model, local leadership, improved seeds, bio-fertilizers, and health management.
- To accelerate indigenous biopharma development in India by encouraging entrepreneurship in biopharma
- Special Features: Rs 1500 crore mission; four verticals; inter-ministerial Steering Committee
Distinguished Biotechnology Research Professorship Award Scheme
- Grants for financial support and research grants to scientists fostering mentorship and leadership of young research groups.
LOTUS-HR Project and DBT-BIRAC Clean Tech Demo Park
- LOTUS-HR Project: Demonstrate holistic management for wastewater to be clean and reusable water.
- DBT-BIRAC Clean Tech Demo Park: Showcase innovative waste-to-value technologies.
- Key Features: A joint India-Netherlands initiative, located at the Barapullah drain site involving various technologies and lots of educational tools.
Source: Annual Report 2023-24, DBT
Programmes
Fellowship and Training
- DBT-JRF (Junior Research Fellowship) Programme: Promotes research and nurtures talent through annual online exams.
- DBT-RA (Research Associateship) Program: Trains young researchers in biotechnology and life sciences (initiated in 1999).
- DBT PG Programme: Supports M.Sc. and M.Tech. programmes in biotechnology and allied areas.
- M K Bhan Fellowship: Provides grants and support for young researchers post-PhD (launched in 2020-21).
- BioCARe Programme: Enhances women’s participation in biotechnology research.
Source: Annual Report 2023-24, DBT
International Collaboration
- Institute of Technology Bombay – Monash Joint PhD Programme: Indo-Australian partnership supporting PhD scholars.
- TWAS Programme: Supports early-career researchers from developing countries (partnership with UNESCO-TWAS).
- DBT-Wellcome Trust Partnership/India Alliance: Promotes biomedical research careers in India.
- EMBO (European Molecular Biology Organization) Membership and Support: Provides fellowships, grants, and workshops for Indian scientists (India became an associate member in 2016).
- HFSPO (Human Science Frontier Programme): Supports interdisciplinary research with high potential (awarded grants and fellowships to Indian researchers in 2023).
- DBT British Council PhD Placement Program: Offers short-term placements for PhD scholars in UK and India.
- Khorana Programmes for Scholars: Provides internships at US labs for Indian pre-final year UG and PG students.
Source: Annual Report 2023-24, DBT
Skill Development and Outreach
- Skill Vigyan Programme: Provides skill training across various domains in biotechnology (executed in 12 states).
- Biotech Industrial Training Programme (BITP): Enhances job opportunities through industry-specific training.
- DBT Star College Programme: Promotes outreach and networking among colleges in Aspirational districts.
- DBT Outreach Programme: Supports conferences, travel, exhibitions, and lectures to raise awareness about biotechnology (includes CTEP component).
- Foldscope Programme: Provides training workshops on using ultra-affordable paper microscopes in schools.
Source: Annual Report 2023-24, DBT
Research Infrastructure
- Research Resources, Service Facilities and Platforms (RRSFP) Programme: Develops research infrastructure with two arms: DBT-BUILDER (upgrades labs) and DBT-SAHAJ (creates national service facilities).
Other Initiatives
- DBT-BUILDER (Boost to University Interdisciplinary Life Science Departments): Upgrades laboratories and enhances interdisciplinary teaching and research capacity.
New Initiatives
Alternatives to Single-Use Plastics
- Research Focus: Corn-based biopolymers, sustainable films/coatings, nano-cellulose, PGGA blends, algae-based plastics, bioconversion of wastes.
- Implementation: Thirty institutions across India.
- Goal: Develop sustainable alternatives to single-use plastics and support plastic waste management.
Key Achievements
- iSMAART: Ceramic membrane integrated anaerobic bioreactor for textile effluent treatment (90% dye decolourization, 70% COD reduction).
- DNA Aptasensor: Point-of-care diagnostic device for E. coli detection in water and urine.
- Marine Biosurfactant: Low-cost production of biosurfactant for oil removal from water.
- Biosurfactant-Mediated Enhanced Oil Recovery: Use of molasses for biosurfactant production in a semi-continuous bioreactor.
References
- Human Frontier Science Program. (n.d.). https://www.hfsp.org/
- India Alliance – Advancing Discovery & Innovation to Improve Health. (n.d.). https://www.indiaalliance.org/
- Integrated Government Online Directory. (n.d.). https://igod.gov.in/organization/d9KpHHUBGGphvn7w1-jZ/SPMA/list
- Joint PhD Program, 2024 | IITB – Monash Research Academy | Apply Now. (n.d.). https://iitbmonash.org/phd_2024/#:~:text=Students%20in%20the%20joint%20IITB,35%2C000%20per%20annum%20in%20Australia.
- Membership, E. (2024, September 11). About EMBO – Membership – EMBO. EMBO. https://www.embo.org/about-embo/membership/
- Newton Bhabha Fund PhD Placements Programme | British Council. (n.d.). https://www.britishcouncil.in/programmes/higher-education/newton-fund/phd-placements
- Welcome to DBT India. (n.d.). https://dbtindia.gov.in/about-us/annual-report/dbt
About the Contributor– Meenu Mohan is a Research Intern at the Impact and Policy Research Institute, and holds a BSMS Degree in Mathematics from IISER, Bhopal.
Acknowledgement– The author extends sincere thanks to Dr. Arjun Kumar, Aasthaba Jadeja, Geetam Acharya, and Shivashish Narayan.
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